Analytical Methods in Environmental Chemistry Journal
AMECJ

A green approach to electrosynthesis of chromeno[3’,4’:5,6] pyrano [2,3-d] pyrimidines

Document Type : Original Article

Author

Reyhaneh Kazemi-Rad
https://doi.org/10.24200/amecj.v1.i01.35
Abstract
Eletrochemistry is a broad, useful, and selective technique method in many research fields. Among them, the investigation of performance of electrochemical methods in determination, synthesis and selective reduction/oxidation of different elements and molecules have attracted growing attention due their intrinsic advantages such as selectivity, low cost, and high yield of synthesis. Moreover, electrocatalytic synthesis of organic molecules is known as a green and environmentally benign method. In the present form, electrocatalytic multicomponent transformation of barbituric acid, aromatic aldehydes, and 4-hydroxycumarin was carried out. The electrocatalytic transformation was done in alcohols in the presence of tetrabutylammounium flouride as an electrolyte in an undivided cell containing an iron electrode as the cathode and a Pt electrode as the anode at a constant current leads to substituted chromeno[3’,4’:5,6] pyrano[2,3-d] pyrimidines in good to high yields (54-92%) at room temperature. The yield of reaction was obtained by gravimetric analysis and calculated upon theoretical conversion.

Graphical Abstract

A green approach to electrosynthesis of chromeno[3’,4’:5,6] pyrano [2,3-d] pyrimidines

Keywords

Analytical methods
Characterization
Electrocatalytic transformation
Chromene
Multicomponent reaction
Pyranopyrimidine
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Analytical Methods in Environmental Chemistry Journal
Volume 1, Issue 1
Autumn 2018
Pages 39-46